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Alfredo Chicken Lasagna

5.0 · 3 reviewsRecipe card by 1 BakerEditorial by recipesvibrant · Updated October 18, 2026
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Alfredo Chicken Lasagna — One Dish Meal recipePin it

Total time

70 min

Servings

1

Calories

529.4

Category

One Dish Meal

This Alfredo Chicken Lasagna combines tender chicken, creamy Alfredo sauce, and three types of cheese for a rich, satisfying one-dish meal that's surprisingly easy to make. With a total time under 70 minutes, it's perfect for busy weeknights or casual entertaining.

Ingredients

Makes 1 serving

  • 6 boneless skinless chicken breasts
  • 1 fresh mushrooms
  • 2 onions
  • 1 garlic clove
  • 1 olive oil
  • 1 all-purpose flour
  • 1 alfredo sauce
  • 3/4 cottage cheese
  • 1/4 parmesan cheese
  • 2 parmesan cheese
  • 1 egg
  • 1/2 dried parsley flakes
  • 1/2 mozzarella cheese

Method

  1. In a large skillet, sauté the chicken, mushrooms, onion and garlic in oil until chicken is no longer pink. Stir in flour until blended; stir in Alfredo sauce. Bring to a boil. Reduce heat; simmer, uncovered, for 5 minutes.

  2. In a small bowl, combine the cottage cheese, 1/4 cup Parmesan cheese, egg, Italian seasoning and parsley. Spread 1/2 cup Alfredo mixture in an 8-in. x 4-in. x 2-in.loaf dish coated with nonstick cooking spray. Layer with two noodles (trimmed to fit pan), half of the cottage cheese mixture, 3/4 cup Alfredo mixture and 3/4 cup mozzarella cheese. Sprinkle with remaining Parmesan cheese. Repeat layers.

  3. Cover and bake at 350°F for 30 minutes. Uncover; bake 10 minutes. Let stand for 10 minutes before cutting.

Cook's notes

  • Use freshly grated Parmesan for the best melt and flavor.
  • Trim lasagna noodles to fit your loaf pan for even layers.
  • Let the lasagna rest for 10 minutes after baking to set the layers.

Easy swaps

  • Instead of boneless skinless chicken breasts, use rotisserie chicken or cooked turkey
  • Instead of fresh mushrooms, use canned mushrooms, drained
  • Instead of cottage cheese, use ricotta cheese
  • Instead of alfredo sauce, use homemade béchamel

Frequently asked

Can I make this gluten-free?

Yes, use gluten-free lasagna noodles and a gluten-free all-purpose flour blend.

What size loaf pan is best?

An 8x4-inch loaf pan works perfectly for this recipe.

Can I add spinach or other vegetables?

Absolutely! Add a layer of sautéed spinach or zucchini for extra nutrition.

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